Hierarchical Structured Component analysis of microRNA-mRNA integration (HisCoM-mimi) model is a novel statistical method to find biological relationship, efficiently study and identify such integrated markers.
HisCoM-mimi could use subgroup information, it yelded more results, as related to phenotypes (e.g. cancer, metabolic syndrome, and etc.), than those of other existing methods that lack network information.
It can be easily applied to other cancer studies to identify miRNA-mRNA integration sets for early diagnosis and prognosis.
Oct 22, 2017 : HisCoM-mimi website opened.
The PHARAOH program has developed by Sungyoung Lee (biznok@gmail.com)
(Interdisciplinary Program in Bioinformatics, Seoul National University, Korea.)