To use HisCoM-mimi, we need to command as following option after installing wisard.
wisard --expression "dataset name" --pharaoh --cv "cv number" --nperm "number of purmutation iteration" --geneset "geneset information file" --out "output name"
For our real dataset, you can obtain your result as following commands.
wisard --expression mimi_dataset.txt --pharaoh --cv 5 --nperm 1000 --geneset annot_mimi.txt --out selected_by_mimi_all_data
Data description [Download]
- mimi_dataset.txt : miRNA and mRNA expression for selected subset
- annot_mimi.txt : miRNA-mRNA integration information
- selected_markers_by_mimi.csv: mRNA, miRNA marker information