HisCoM-PCA
BIBS lab, Seoul National University
Hierarchical Structural Component Models of Pathway A
nalysis using Pathway analysis of Common vAriants(HisCoM-PCA) is a novel pathway analysis method for common variants in GWAS
HisCoM-PCA is based on Principal Component Analysis (PCA) for dimension reduction of SNPs in each gene, and the hierarchical structural component model (HisCoM) for pathway analysis.
HisCoM-PCA analyzes entire pathways simultaneously by ridge-type penalization of both the gene and pathway effects on the phenotype
Maintenance
If there is error, please let us know about the running problem to solve the problem and improve our program.
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