Pathway-based approach using HierArchical structure of collapsed RAre variants Of High-throughput sequencing data for Multiple phenotypes (PHARAOH-Multi) is a novel statistical approach for multivariate analysis of rare variants using pathway information.
PHARAOH-Multi is possible to investigate an association between multiple phenotypes and each pathway or entire pathways simultaneously, regarding the relatedness across entire pathways, using collapsed rare variants using gene information.
PHARAOH-Multi implemented doubly ridge method for an analysis of entire pathways.
Jan 1, 2017 : PHARAOH-Multi website opened.
The PHARAOH program has developed by Sungyoung Lee (email@example.com)
(Interdisciplinary Program of Bioinformatics, Seoul National University, Korea.)