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IGENT is an efficient algorithm for identifying genome-wide gene-gene interactions (GGI) and gene-environment interaction (GEI). IGENT supports two types of strategies to identify gene-gene interactions related with diseases in genome-wide scale. One is an exhaustive search approach for lower-order interactions such as 2nd order interaction, and the other is a stepwise selection approach for higher-order interaction. With tens of thousands of SNPs from thousands of samples, it is difficult to calculate higher-order interaction exhaustively because the computational burden is too heavy. IGENT provides a stepwise approach for higher-order interactions.
IGENT is currently at Version 1.5 (04/19/2017)